Partial Meniscus Replacement with a Collagen-Hyaluronan Infused Three-Dimensional Printed Polymeric Scaffold
نویسندگان
چکیده
منابع مشابه
Development of a Tissue Engineered Scaffold for Meniscus Replacement
It is well accepted that the loss of meniscal function due to surgical removal is a significant factor in the onset of degenerative osteoarthritis of the knee. Few viable alternatives exist for the replacement of significantly damaged tissue. In this study, two potential designs for meniscus scaffolds were compared with a focus on the mechanical protection they provide the articular surfaces an...
متن کاملIn Vitro Testing of Modified Collagen/ Hyaluronan/beta-glucan Scaffold
Cells and scaffolds belong to main components of tissue engineering. In this study we have performed in vitro cytotoxicity and biocompatibility testing of modified collagen/hyaluronan/beta-glucan scaffold. We used direct contact assay as well as MTT test. Human adipose tissue-derived stem cells were used as biological model. According to obtained results, we can summarize, that modified collage...
متن کاملA three-dimensional collagen scaffold cell culture system for screening anti-glioma therapeutics
Three-dimensional (3D) culture, which can simulate in vivo microenvironments, has been increasingly used to study tumor cell biology. Since most preclinical anti-glioma drug tests still rely on conventional 2D cell culture, we established a collagen scaffold for 3D glioma cell culture. Glioma cells cultured on these 3D scaffolds showed greater degree of dedifferentiation and quiescence than cel...
متن کاملOsteogenic Differentiation of Mesenchymal Stem Cells Induced by Mechanical Strain in a Three Dimensional Collagen Scaffold
Introduction Most body tissues are subjected to physical forces. The effects of biophysical force on bone remodeling have become increasingly evident in recent years. It is well known that extended periods of immobilization lead to bone loss. Mechanical loading is one of the few positive stimuli for bone formation, and the use of suitable exercise regimes has been proposed as being potentially ...
متن کاملExpanded human meniscus-derived cells in 3-D polymer-hyaluronan scaffolds for meniscus repair.
Treatment options for lesions of the avascular region of the meniscus using regenerative medicine approaches based on resorbable scaffolds are rare. Recent approaches using scaffold-based techniques for tissue regeneration known from cartilage repair may be a promising treatment option for meniscal tears. The aim of the study was the investigation of meniscus matrix formation of in vitro expand...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2019
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2018.0160